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Tigliane diterpenoids from the stem bark of Neoboutonia macrocalyx.

Kirira PG, Rukunga GM, Wanyonyi AW, Muthaura CN, Mungai GM, Machocho AK, Ndiege IO

Department of Chemistry, School of Pure and Applied Sciences, Kenyatta University, P.O. Box 43844, Nairobi 00100, Kenya.

Neoboutonia macrocalyx is a plant used by traditional healers among the Meru community in Kenya. Chromatographic fractionation of the petroleum ether and dichloromethane extracts of this plant yielded one known (1) and three new tigliane-type diterpenoids (2-4). The chemical structures of the isolated compounds were established through spectroscopic data interpretation.

Published 25 May 2007 in J Nat Prod, 70(5): 842-5.
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